Exact Sciences Corporation

Lab Service and Applications Engineer II

Job Locations US-AZ-Phoenix
Req No.
Clinical Lab Operations
Regular Full-Time

Summary of Major Responsibilities

As a member of our Service and Applications Engineering team, this Service Engineer II is responsible for service and applications support of complex robotic workstations, qPCR instruments, as well as other laboratory equipment.  He or she will conduct preventative maintenance and troubleshoot instrument problems by performing root cause analysis, implementing and documenting appropriate corrective actions, while maintaining instruments to peak performance for Exact Sciences Precision Oncology’s various laboratory environments. These environments include the Clinical Laboratory where our industry-leading Oncotype DX® clinical diagnostic assays are run, the R&D laboratories where new product concepts are developed, and our Manufacturing and QC laboratories, which provide high-quality reagents for use in the other lab functions within Exact Sciences.


The successful candidate will have hands-on experience with liquid handling robotics and an in-depth understanding of current laboratory instruments used for nucleic acid isolation, quantification, and downstream analysis using quantitative RT-PCR.  Activities will include responding to instrument-related errors, performing root cause analysis to identify the problem, and implementing an appropriate corrective action to repair the instrument in a time-critical customer service-oriented manner.  He or she will be expected to develop a working knowledge of all Exact Sciences laboratory processes and associated systems such as our Laboratory Information Management Systems (LIMS). 

This Service Engineer II will participate in cross-functional teams working in a variety of areas.  These efforts will require excellent communication and collaboration with colleagues in Process Engineering, Assay Chemistry, our Clinical and Development Laboratories, Program Management, Research, Analytical Sciences, Manufacturing, Quality Assurance, and other groups. 


The ideal candidate will be working cooperatively in a dynamic and interdisciplinary laboratory environment, adapting quickly to change and new technical challenges while providing strong technical leadership.  This is an excellent opportunity for a team player to participate in the growth of a fast-paced, pioneering company that is developing systematic approaches to applying genomic technology to health, disease, and medical practice.

Essential Duties and Responsibilities

  • Provide service and applications support to multiple laboratories at the Precision Oncology Division of Exact Sciences.
  • Maintain, calibrate, and perform equipment preventative maintenance.
  • Troubleshoot, diagnose and resolve hardware, software, and chemistry issues of robotic workstations, qPCR instruments, and other laboratory equipment.
  • Participate in 24/7 week-long on-call rotation with other team members.
  • Coordinate and/or perform instrument installations and qualifications.
  • Write or revise detailed standard operating procedures (SOP’s) for processes performed by the Service Engineering group.
  • Assist with transferring and testing of new robotic processes.
  • Represent the Service Engineering group on cross-functional teams.
  • Train members of the Service Engineering team on processes in areas of expertise to enhance and contribute group development and cross-training, as needed.
  • Participate in the development of in-house qualification procedures and other supporting documentation.
  • Maintain positive customer and service-oriented interactions with customers and colleagues.
  • Perform daily work and projects with limited or general instructions, according to the SOPs.
  • Capability to drive professional development by mastering instrument and assay related troubleshooting, preventative maintenance, and qualification procedures.
  • Strong attention to detail.
  • Robust problem-solving skills.
  • Ability to write or revise detailed SOP’s for processes performed by the Service Engineering group.
  • Ability to maintain flexibility and prioritize work schedule to support instrument up-time and sample throughput.
  • Ability to quickly adopt and apply new methods and technologies.
  • Ability to implement process improvements identified in workflows in collaboration with the manager.
  • Excellent interpersonal skills.
  • Excellent communication skills (both written and verbal).
  • Ability to maintain open communication with internal employees, managers, and customers, as needed.
  • Ability to integrate and apply feedback in a professional manner.
  • Ability to prioritize and drive to results with a high emphasis on quality.
  • Ability to work as part of a team.
  • Uphold company mission and values through accountability, innovation, integrity, quality, and teamwork.
  • Support and comply with the company’s Quality Management System policies and procedures.
  • Regular and reliable attendance.


Minimum Qualifications

  • Bachelor’s degree in a relevant scientific or engineering field; or high school degree/general education diploma and 4 years of relevant experience in lieu of a degree.
  • 3+ years of relevant experience in use and support of laboratory/medical equipment
  • 3+ years of experience with Quality Systems and documentation requirements.
  • Working knowledge of database, laboratory information management systems, and other file management applications.
  • Demonstrated ability to perform the Essential Duties of the position with or without accommodation.
  • Authorization to work in the United States without sponsorship.

Preferred Qualifications

  • Bachelor's Degree in a relevant scientific or engineering field
  • 2+ years of experience with standard molecular biology techniques such as nucleic acid isolation, RNA/DNA quantification, PCR and RT-PCR
  • 3+ years of relevant experience in use and support of automated liquid handlers.
  • Demonstrated mechanical aptitude relevant to automated liquid handlers and other general laboratory equipment.
  • Good knowledge of automated liquid handler scripting software.
  • Experience with Next-Generation Sequencing (NGS).
  • Experience with Digital Pathology Imagining.

We are an equal employment opportunity employer. All qualified applicants will receive consideration for employment without regard to age, color, creed, disability, gender identity, national origin, protected veteran status, race, religion, sex, sexual orientation, and any other status protected by applicable local, state or federal law. Applicable portions of the Company’s affirmative action program are available to any applicant or employee for inspection upon request.


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